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The 2001 anthrax attacks in the United States, also known as Amerithrax from its FBI case name, occurred over the course of several weeks beginning on September 18, 2001. Letters containing anthrax spores were mailed to several news media offices and two Democratic U.S. Senators, killing five people and infecting 17 others. As a response, the US increased countermeasure research funding and funding into the public health sector. Before the BioWatch program, the quickest method of detecting the presence of an infectious material was through the diagnosis of infected patients, however the most effective treatment takes place prior to infection or in its early stages.[1] While the Central Intelligence Agency maintains that the use of bioterrorism in the United States is unlikely,[3] the Biowatch program was created in 2001 in conjunction with the FBI, EPA, United States Department of Homeland Security and the US Laboratory Response Network for Bioterrorism, and was tested by the Centers for Disease Control and Prevention and Association of Public Health Laboratories. According to the DHS, the BioWatch program helps to provide "early warning of a mass pathogen release."[1] The original 31 city program cost $60 million to implement, with a proposed expansion in 2005 to cost $118 million.

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